What is Zollinger-Ellison Syndrome?

An uncommon disorder resulting in diarrhea and multiple peptic ulcers. The cause is a pancreatic tumor or enlarged pancreas, which in turn lead to high levels of the hormone gastrin, which stimulates excess production acidic gastric juice, causing the ulceration. Surgery is usually effective.

Endoscopic image of multiple small ulcers located in the distal duodenum in a patient with Zollinger-Ellison syndrome.